Supernova SN 2023ixf in upper outer arm of M101.
M101 - the Pinwheel Galaxy is a large spiral galaxy 21 million light-years from Earth. Approx. 170,000 light-years in diameter, it is home to about 1 trillion stars.
The Galaxy has a high population of HII (ionised hydrogen) regions, which appear as bright red spots in the spiral arms. These are regions of new star formation and are illuminated by extremely bright and hot young stars.
The asymmetry in the spiral arms is due to gravitational interaction with companion galaxies, including NGC5474 which can be seen in the bottom right of the picture. The interaction is also thought to have created the distortion in this dwarf galaxy.
On 19/05/2023 a supernova was discovered in M101 by amateur astronomer Koichi Itagaki. The animation here shows M101 about a fortnight later on the 03/06/2023 from a back garden in Leeds, compared to the previous year.
For more info. see the Wikipedia entry.